I'll take my fourth dose this evening. I've had a couple of headaches that I'm not sure I can attribute to the drug - it could be the excessive heat we've been experiencing lately. No other side effects at this time, other than being extremely thirsty! However, this morning I woke up to see that some of the cystic acne along my jawline (which has been there for months) was Greatly reduced in size - some of it even gone! Wow! I am still seeing new breakouts, but I was really excited to see that improvement.